And no none of these are self shots. In Peyronie's disease, fibrous scar tissue develops under the skin of the penis. The cause of this fibrous tissue is not known. Fracture of the penis (injury during intercourse) can lead to this condition. Patients have a higher risk after surgery or radiation treatment for prostate cancer. Peyronie's disease is uncommon and affects men ages 40 - 60 and older. Curvature of the penis can occur with Dupuytren's contracture, a cord-like thickening across the palm of one or both hands. It is a fairly common disorder in white men over age 50. However, only a very small number of people with Dupuytren's contracture develop curvature of the penis. Other risk factors have not been found. However, people with this condition have a certain type of immune cell marker, which indicates that it may be inherited. Newborns may have a curvature of the penis, which may be part of an abnormality called hypospadias (this is different from Peyronie's disease).